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ICMT Antibody (PA5-85576) in IHC (P)
ICMT Polyclonal Antibody detects ICMT protein at cytosol on mouse hind brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse hind brain. ICMT Polyclonal Antibody (Product # PA5-85576) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-85576
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human ICMT.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2792716
产品详细信息
Keep as concentrated solution.
Predicted reactivity: Pig (100%).
Positive Control: HeLa membrane extract (unboiled).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes the third of three enzymes that post translationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Farnesyl cysteine carboxyl methyltransferase; FCMT; Isoprenylcysteine carboxylmethyltransferase; MGC39955; pcCMT; PPMT; Prenylated protein carboxyl methyltransferase; prenylcysteine carboxyl methlytransferase; Prenylcysteine carboxyl methyltransferase; protein-S isoprenylcysteine O-methyltransferase; Protein-S-isoprenylcysteine O-methyltransferase
基因别名: 1700008E11Rik; C80758; fcmt; Gm13095; HSTE14; ICMT; MST098; MSTP098; OTTMUSG00000010406; PCCMT; PCMT; PPMT; STE14
UniProt ID: (Human) O60725, (Rat) Q9WVM4, (Mouse) Q9EQK7
Entrez Gene ID: (Human) 23463, (Rat) 170818, (Mouse) 57295
cellular protein modification process
C-terminal protein methylation
protein targeting to membrane
post-translational protein modification
S-adenosylhomocysteine metabolic process
S-adenosylmethioninamine metabolic process
in utero embryonic development
liver development
protein methylation
protein localization
positive regulation of cell proliferation
multicellular organism growth
regulation of Ras protein signal transduction
regulation of nucleic acid-templated transcription
regulation of RNA biosynthetic process
methylation
