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ICOS (CD278) Antibody (MA5-16415) in IHC (P)
Immunohistochemical (paraffin) analysis of CD278/ICOS (CD278) using anti-CD278/ICOS (CD278) Monoclonal Antibody (Product # MA5-16415) in Reactive Lymph Node Tissue. The recommended dilution for this antibody in immunohistochemistry applications is 1:100.
产品信息
MA5-16415
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Monoclonal
类型
Antibody
克隆号
SP98
抗原
Synthetic peptide corresponding to the C-terminus of human CD278
偶联物
形式
Liquid
浓度
Conc. not determined
纯化类型
Protein A/G
保存液
PBS, pH 7.6, with 1% BSA
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2537934
产品详细信息
Heat-mediated antigen retrieval is recommended prior to staining, using a 1mM EDTA buffer, pH 8.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggested positive control is tonsil or reactive lymph node tissue.
靶标信息
ICOS (CD278) encodes a protein that is a member of the CD28 and CTLA-4 cell-surface receptor family. It functions as a homodimer and has a crucial role in cell-cell signaling, immune responses, and the regulation of cell proliferation. ICOS has been linked to various disorders, including Immunodeficiency, Common Variable, 1 and Common Variable Immunodeficiency.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Activation-inducible lymphocyte immunomediatory molecule; CD278; inducible costimulator; inducible T-cell co-stimulator; Inducible T-cell costimulator
基因别名: AILIM; CD278; CVID1; ICOS
UniProt ID: (Human) Q9Y6W8
Entrez Gene ID: (Human) 29851
