NeoBiotechnologies

ID1 (Inhibitor of DNA-binding) (Transcription Factor) Monoclonal Antibody (PCRP-ID1-2F11)

ID1 (Inhibitor of DNA-binding) (Transcription Factor) Antibody in Immunocytochemistry (ICC/IF)

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ID1 (Inhibitor of DNA-binding) (Transcription Factor) Antibody (3397-MSM3-P1ABX) in ICC/IF

Immunofluorescence analysis of PFA-fixed HeLa cells stained using ID1 Mouse Monoclonal Antibody (PCRP-ID1-2F11). followed by goat anti-mouse IgG-CF488 (green). CF640A phalloidin (red).

ID1 (Inhibitor of DNA-binding) (Transcription Factor) Antibody in Flow Cytometry (Flow)

ID1 (Inhibitor of DNA-binding) (Transcription Factor) Antibody in Peptide array (ARRAY)

ID1 (Inhibitor of DNA-binding) (Transcription Factor) Antibody in SDS-PAGE (SDS-PAGE)

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产品信息

3397-MSM3-P1ABX

应用

建议稀释比

已发表文章

免疫细胞化学 (ICC/IF)

1-2 µg/mL

流式细胞分析 (Flow)

1-2 µg/10^6 cells

酶联免疫吸附实验 (ELISA)

Assay-dependent

免疫沉淀 (IP)

1-2 µg/100-500 µg total protein

肽阵列 (Array)

Assay-dependent

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

PCRP-ID1-2F11

抗原

Recombinant fragment (aa 5-150) of human ID1

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A/G

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

ID1 is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. It has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene.The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: bHLHb24; Class B basic helix-loop-helix protein 24; dJ857M17.1.2; dJ857M17.1.2 (inhibitor of DNA binding 1, dominant negative helix-loop-helix protein); DNA-binding protein inhibitor ID-1; Inhibitor of differentiation 1; Inhibitor of DNA binding 1; inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

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基因别名: BHLHB24; ID; ID1

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UniProt ID: (Human) P41134

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Entrez Gene ID: (Human) 3397

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功能

transcription factor activity, sequence-specific DNA binding protein binding protein C-terminus binding transcription factor binding protein homodimerization activity protein self-association protein N-terminus binding proteasome binding DNA-binding transcription factor

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