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Recommended positive controls: HCT116.
Predicted reactivity: Mouse (98%), Rat (97%), Xenopus laevis (82%), Pig (98%), Chicken (94%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The inhibitor of DNA binding 2 (ID2) protein is essential for promoting the development of a number of cell types including natural killer cell, erythroid precursors, as well as, CD8+ and CD4+ T-cell. A lack of ID2 promotes B-cell development. The chief role of this protein is to associate with ubiquitously-expressed E proteins, and other proteins of the basic helix-loop-helix (HLH) family, preventing them from binding to DNA and activating transcription. Activation of ID2 is critical for the development of the natural killer cell lineage.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: bHLHb26; cell growth-inhibiting gene 8; Class B basic helix-loop-helix protein 26; DNA-binding protein inhibitor ID-2; DNA-binding protein inhibitor ID2; helix-loop-helix protein ID2; Inhibitor of differentiation 2; Inhibitor of DNA binding 2; Inhibitor of DNA binding 2, dominant negative helix-loop-helix protein; MGC26389; OTTHUMP00000140258; OTTHUMP00000200297
基因别名: Ac2-300; AI255428; BHLHB26; C78922; GIG8; Id-2; ID2; ID2A; ID2H; Idb2
UniProt ID: (Human) Q02363, (Rat) P41137, (Mouse) P41136
Entrez Gene ID: (Human) 3398, (Rat) 25587, (Mouse) 15902