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产品信息
PA5-66128
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2661985
产品详细信息
Immunogen sequence: ANTDTRPGNLH GAFRGLRTDC SRSALNLSHS ELEEGGSFST RIRSHSTIRT LAFPQGNAFT IRTANGGYKF RWV
Highest antigen sequence identity to the following orthologs - mouse 81%, rat 78%.
靶标信息
Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway (PubMed:25048963). Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1 (PubMed:21543332, PubMed:24064211).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: McIdas protein; multiciliate cell differentiation 1; Multiciliate differentiation and DNA synthesis-associated cell cycle protein; Multicilin; Protein Idas
基因别名: IDAS; MCI; MCIDAS; MCIN
UniProt ID: (Human) D6RGH6
Entrez Gene ID: (Human) 345643
