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产品信息
PA5-142772
产品规格
种属反应
Human,
Pig,
Rat
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence C-DHLKLHSYATSIRK (aa 337-350).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2933418
产品详细信息
Additional Information: This antibody is expected to recognize both reported isoforms (NP_004126.1; NP_777358.1).
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
靶标信息
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: IDH-gamma; iso; isocitrate dehydrogenase (NAD(+)) 3 gamma; isocitrate dehydrogenase 3 (NAD(+)) gamma; isocitrate dehydrogenase 3 (NAD+) gamma; isocitrate dehydrogenase 3 gamma; isocitrate dehydrogenase 3, gamma; isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial; Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial; isocitrate dehydrogenase, NAD(+)-specific, mitochondrial, gamma subunit; Isocitric dehydrogenase subunit gamma; NAD (H)-specific isocitrate dehydrogenase gamma subunit; NAD(+)-specific ICDH subunit gamma; NAD+-isocitrate dehydrogenase gamma subunit; NAD+-specific ICDH
基因别名: H-IDHG; IDH; IDH3G
UniProt ID: (Human) P51553
Entrez Gene ID: (Pig) 100525850, (Human) 3421, (Rat) 25179
