Search Thermo Fisher Scientific
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAVTTRLTRL HEKILQNHFG GKRLSLLYKG SVHGFRNGVL LDRCCNQGPT LTVIYSEDHI IGAYAEESYQ EGKYASIILF ALQDTKISEW KLGLCTPETL FCCDVTKYNS PTNFQIDGRN RKVIMDLKTM ENLGLAQNCT ISIQDYEVFR CEDSLDERKI KGVIELRKSL LSALRTYEPY GSLVQQIRIL LLGPIGAGKS SFFNSVRSVF QGHVTHQALV GTNTTGISEK YRTYSIRDGK DGKYLPFILC DSLGLSEKEG GLCRDDIFYI LNGNIRDRYQ FNPMESIKLN HHDYIDSPSL KDRIHCVAFV FDASSIQYFS SQMIVKIKRI RRELVNAGVV HVALLTHVDS MDLITKGDLI EIERCEPVRS KLEEVQRKLG FALSDISVVS NYSSEWELDP VKDVLILSAL RRMLWAADDF LEDLPFEQIG NLREEIINCA QGKK
IFI-44 (interferon-induced protein 44), also known as p44 or MTAP44 (microtubule-associated protein 44), is a 444 amino acid protein that localizes to the cytoplasm and, upon induction by IFN-βs, aggregates to form microtubular structures. Human IFI-44 shares 97% sequence similarity with its chimp counterpart, suggesting a conserved role between species. The gene encoding IFI-44 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Interferon-induced protein 44; interferon-induced, hepatitis C-associated microtubular aggregate protein (44kD); Microtubule-associated protein 44; p44; TBC/LysM-associated domain containing 5
基因别名: IFI44; MTAP44; p44; TLDC5
UniProt ID: (Human) Q8TCB0
Entrez Gene ID: (Human) 10561