Invitrogen

IFN alpha Polyclonal Antibody

IFN alpha Antibody in Immunocytochemistry (ICC/IF)

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IFN alpha Antibody (PA5-115430) in ICC/IF

Immunocytochemistry analysis of IFN alpha in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115430) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goat a... View More

IFN alpha Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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产品信息

PA5-115430

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

1:100-1:500

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthesized peptide derived from human IFNA1; IFNA13(Accession P01562), corresponding to amino acid residues S21-F71.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity chromatography

保存液

PBS with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

AB_2900066

产品详细信息

Antibody detects endogenous levels of total Interferon alpha 1.

靶标信息

IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN-alpha with its receptor component result in the activation of a number of signaling pathways which are mainly involved in innate immune response against viral infection. In humans, the gene for IFN alpha is located on on chromosome 9. The type I interferons consist of 14 different alpha isoforms (subtypes with slightly different specificities), and single beta, omega, epsilon and kappa isoforms. Homologous molecules are found in many species, including rats and mice (and most mammals), and have been identified in birds, reptiles and fish species. IFN alpha is produced primarily by plasmacytoid dendritic cells, is a potent component of the anti-viral innate immune response and modulates adaptive immunity. Diseases associated with the dysfunction of IFN alpha include Hepatitis C and Hepatitis.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: alpha-2a interferon; ifa; IFN alpha 1/13; IFN alpha 1b; IFN α; IFN-alpha 1b; IFN-alpha-1; IFN-alpha-1/13; IFN-alpha-2; IFNAalphaIFN-alpha-1/13; IFNalpha; IFNα; Interferon alpha 13 (IFNA13); interferon alpha 15; interferon alpha 1b; interferon alpha 2a; interferon alpha 2b; interferon alpha A; interferon alpha family gene 1; interferon alpha family, gene 2; Interferon alpha leukocyte (IFL); Interferon alpha-1; Interferon alpha-1/13; Interferon alpha-1/13 (IFN-alpha-1/13); Interferon alpha-2; Interferon alpha-A; Interferon alpha-D; Interferon alpha-D (IFN alphaD); Interferon alpha1 (IFNA1); interferon, alpha 1; interferon, alpha 2; interferon-alpha1; LeIF A; LeIF D; MGC138207; MGC138505; MGC138507; novel interferon alpha (Ifna) family member

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基因别名: Gm12597; Ifa1; Ifa2; IFL; IFN; IFN-ALPHA; IFN-alpha1; IFN-alphaA; IFN-alphaD; IFNA; IFNA1; IFNA13; IFNA2; IFNA2A; IFNA2B; IFNA2C; IFNA@; Ifnaa; INFA2; MuIFN-alpha-A; OTTMUSG00000007655