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产品信息
MA5-24415
产品规格
种属反应
Human
已发表种属
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
3F9
抗原
IFNA13 (NP_008831, 91 a.a. ~ 189 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
1.0 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2633387
产品详细信息
Peptide Sequence: FTTKDSSAAW DEDLLDKFCT ELYQQLNDLE ACVMQEERVG ETPLMNADSI LAVKKYFRRI TLYLTEKKYS PCAWEVVRAE IMRSLSLSTN LQERLRRKE
靶标信息
Interferon alpha (IFN alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN-alpha with its receptor component results in the activation of a number of signaling pathways which are mainly involved in innate immune response against viral infection. In humans, the gene is located on on chromosome 9. The type I interferons consist of 14 different alpha isoforms (subtypes with slightly different specificities), and single beta, omega, epsilon and kappa isoforms. Homologous molecules are found in many species, including rats and mice (and most mammals), and have been identified in birds, reptiles and fish species. Interferon alpha is produced primarily by plasmacytoid dendritic cells and is a potent component of the anti viral innate immune response; it modulates adaptive immunity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: IFN-alpha 1b; IFN-alpha-1/13; Interferon; interferon alpha 1b; Interferon alpha-1/13; Interferon alpha-D; interferon, alpha 13; interferon-alpha1; LeIF D
基因别名: IFNA1; IFNA13
UniProt ID: (Human) P01562
Entrez Gene ID: (Human) 3447
adaptive immune response
T cell activation involved in immune response
natural killer cell activation involved in immune response
humoral immune response
blood coagulation
cytokine-mediated signaling pathway
B cell differentiation
positive regulation of peptidyl-serine phosphorylation of STAT protein
B cell proliferation
response to exogenous dsRNA
innate immune response
defense response to virus
type I interferon signaling pathway
regulation of type I interferon-mediated signaling pathway
