Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 2
IFT122 Antibody (PA5-148291) in ICC/IF
Immunocytochemistry analysis of IFT122 in A431 cells. Samples were incubated with IFT122 polyclonal antibody (Product # PA5-148291) using a dilution of 1:200 at 4°C overnight followed by Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Cells were fixed with 4% PFA, permeabilized with 0.1% Triton X-100 in PBS, and blocked with 10% serum. Counterstained with DAPI (blue). Positive staining was localized to Cytoplasm.
产品信息
PA5-148291
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
E. coli-derived Human IFT122 fragment
偶联物
形式
Liquid
浓度
100 µg/mL
纯化类型
Antigen affinity chromatography, Protein A
保存液
PBS, pH 7
内含物
0.03% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This cytoplasmic protein contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: intraflagellar transport 122 homolog; Intraflagellar transport protein 122 homolog; WD repeat domain 10; WD repeat-containing protein 10; WD repeat-containing protein 140
基因别名: CED; CED1; IFT122; SPG; WDR10; WDR10p; WDR140
UniProt ID: (Human) Q9HBG6
Entrez Gene ID: (Human) 55764
neural tube closure
signal transduction downstream of smoothened
embryonic body morphogenesis
negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
embryonic heart tube development
embryonic forelimb morphogenesis
intraciliary anterograde transport
intraciliary retrograde transport
intraciliary transport involved in cilium morphogenesis
cilium assembly
embryonic digit morphogenesis
negative regulation of smoothened signaling pathway
camera-type eye morphogenesis
negative regulation of epithelial cell proliferation
limb development
cilium morphogenesis
ciliary receptor clustering involved in smoothened signaling pathway
smoothened signaling pathway involved in dorsal/ventral neural tube patterning
embryonic heart tube left/right pattern formation
protein localization to cilium
establishment of protein localization to organelle
