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IFT88 Antibody (MA5-55471) in WB
Western Blot analysis of various lysates using IFT88 Recombinant Monoclonal Antibody (Product # MA5-55471) at 1:1,000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
产品信息
MA5-55471
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
6P4S5
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 534-833 of human IFT88.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20° C, Avoid Freeze/Thaw Cycles
产品详细信息
Immunogen Sequence: GLTYEKLNRL DEALDCFLKL HAILRNSAEV LYQIANIYEL MENPSQAIEW LMQVVSVIPT DPQVLSKLGE LYDREGDKSQ AFQYYYESYR YFPCNIEVIE WLGAYYIDTQ FWEKAIQYFE RASLIQPTQV KWQLMVASCF RRSGNYQKAL DTYKDTHRKF PENVECLRFL VRLCTDLGLK DAQEYARKLK RLEKMKEIRE QRIKSGRDGS GGSRGKREGS ASGDSGQNYS ASSKGERLSA RLRALPGTNE PYESSSNKEI DASYVDPLGP QIERPKTAAK KRIDEDDFAD EELGDDLLPE
靶标信息
This gene encodes a member of the tetratrico peptide repeat family. Mutations of a similar gene in mouse can cause polycystic kidney disease. Two transcript variants encoding distinct isoforms have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HGNC:20606; intraflagellar transport 88 homolog; Intraflagellar transport protein 88 homolog; MGC26259; polaris homolog; probe hTg737 (polycystic kidney disease, autosomal recessive); Recessive polycystic kidney disease protein Tg737; Recessive polycystic kidney disease protein Tg737 homolog; RP11-172H24.2; testicular tissue protein Li 93; tetratricopeptide repeat domain 10; Tetratricopeptide repeat protein 10; Tg737 protein; TgN(Imorpk)737Rpw; TPR repeat protein 10; transgene insert site 737, insertional mutation, polycystic kidney disease
基因别名: AW552028; D13S1056E; DAF19; flexo; fxo; hTg737; IFT88; orpk; polaris; TG737; Tg737Rpw; TgN737Rpw; TTC10
UniProt ID: (Human) Q13099, (Mouse) Q61371
Entrez Gene ID: (Human) 8100, (Mouse) 21821, (Rat) 305918
cilium morphogenesis
regulation of cilium assembly
regulation of autophagosome assembly
eye development
kidney development
liver development
epithelial cell morphogenesis
Notch signaling pathway
smoothened signaling pathway
sperm axoneme assembly
spermatid nucleus elongation
determination of left/right symmetry
nervous system development
brain development
heart development
protein localization
epidermis development
regulation of smoothened signaling pathway
organ morphogenesis
anterior/posterior pattern specification
dorsal/ventral pattern formation
spinal cord dorsal/ventral patterning
telencephalon development
cell projection organization
lung development
pancreas development
cytoplasmic microtubule organization
response to fluid shear stress
nonmotile primary cilium assembly
epidermal stem cell homeostasis
cilium assembly
regulation of odontogenesis of dentin-containing tooth
embryonic digit morphogenesis
positive regulation of insulin-like growth factor receptor signaling pathway
regulation of fat cell differentiation
forebrain morphogenesis
negative regulation of epithelial cell proliferation
cardiac muscle cell differentiation
palate development
inner ear receptor stereocilium organization
limb development
regulation of feeding behavior
cardiac septum morphogenesis
lung vasculature development
heart formation
neural precursor cell proliferation
regulation of protein processing
cochlea development
