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产品信息
PA5-51429
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2642654
产品详细信息
Immunogen sequence: AYPSLVAMAS QRQAKIQRYK QKKELEHRLS AMKSAVESGQ ADDERVREYY LLHLQRWIDI SLEEIESIDQ EIKILRERDS SREASTSNSS RQERPPVKPF ILTRNMAQAK VFGAGYPSLP
Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 83%.
靶标信息
The proliferation and differentiation of B cells is dependent upon a B-cell antigen receptor (BCR) complex. Binding of antigens to specific B-cell receptors results in a tyrosine phosphorylation reaction through the BCR complex and leads to multiple signal transduction pathways.
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生物信息学
蛋白别名: B cell signal transduction molecule alpha 4; B-cell signal transduction molecule alpha 4; bA351K23.1 (immunoglobulin binding protein 1 (CD79A) ); CD79a-binding protein 1; Immunoglobulin-binding protein 1; Protein alpha-4; Protein phosphatase 2/4/6 regulatory subunit; protein phosphatase 2A, regulatory subunit alpha-4; Renal carcinoma antigen NY-REN-16
基因别名: ALPHA-4; IBP1; IGBP1
UniProt ID: (Human) P78318
Entrez Gene ID: (Human) 3476
negative regulation of transcription from RNA polymerase II promoter
signal transduction
negative regulation of stress-activated MAPK cascade
regulation of protein phosphatase type 2A activity
response to tumor necrosis factor
positive regulation of dephosphorylation
negative regulation of protein dephosphorylation
B cell activation
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of transcription from RNA polymerase II promoter
regulation of microtubule-based movement
response to interleukin-1
negative regulation of apoptotic signaling pathway
