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IGF2BP3 Antibody (MA5-27481) in ICC/IF
Immunofluorescence analysis of IGF2BP3 was performed using IMR-32 and MCF7 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with IGF2BP3 Mouse Monoclonal Antibody (Product # MA5-27481) at 1:100 dilution in 0.1% BSA and incubated overnight at 4 degree and then labeled with Goat anti-Mouse IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Product # A32723) at a diluti... View More
产品信息
MA5-27481
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
OTI7B10
抗原
Full length human recombinant protein of IGF2BP3 produced in E.coli
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2723272
靶标信息
Insulin-like growth factor-II messenger RNA (mRNA)-binding protein-3 (IMP-3), also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, is a member of the insulin-like growth factor-II mRNA-binding protein family and is expressed during embryogenesis and in some malignancies. IMP-3 is expressed in malignant melanoma but not in benign nevi, even when dysplastic features are present; IMP-3 is expressed in a significantly higher proportion of melanomas than Spitz nevi; and IMP-3 is expressed in metastatic melanomas significantly more than in thin melanomas. IMP-3 appears to be involved in the progression of malignant melanoma and may play an important role in the regulation of the biologic behavior of this tumor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cancer/testis antigen 98; hKOC; IGF-II mRNA-binding protein 3; IGF2 mRNA-binding protein 3; insulin-l; insulin-like growth factor 2 mRNA binding protein 3; Insulin-like growth factor 2 mRNA-binding protein 3; insulin-like growth factor 2, binding protein 3; KH domain containing protein overexpressed in cancer; KH domain-containing protein overexpressed in cancer; mIMP-3; VICKZ family member 3
基因别名: 2610101N11Rik; AA522010; Ab2-255; AL022933; AU045931; CT98; IGF2BP3; IMP-3; IMP3; KOC; KOC1; Koc13; mimp3; Neilsen; RGD1306512; VICKZ3
UniProt ID: (Human) O00425, (Mouse) Q9CPN8
Entrez Gene ID: (Human) 10643, (Mouse) 140488, (Rat) 312320
