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This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Mouse IGFBP-2/IGFBP2.
IGFBP2 (insulin-like growth factor binding protein 2) is a member of the ISGBP family which bind various IGFs. IGFBP2 is overexpressed in a wide spectrum of cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The overexpression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: IBP-2; IGF binding protein 2; IGF-binding protein 2; IGFBP; Insulin like growth factor binding protein; Insulin-like growth factor-binding protein 2; OTTHUMP00000207753
基因别名: AI255832; IBP-2; Igfbp-2; Igfbp2; mIGFBP-2
UniProt ID: (Mouse) P47877
Entrez Gene ID: (Mouse) 16008