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IHH Antibody (PA5-19680) in WB
Western blot analysis of Mouse Colon Tissue Lysate using Product # PA5-19680, Ihh primary antibody at a dilution of 1 µg/mL (lane 1). Staining of NIH 3T3 Whole Cell Lysate at a dilution of 1 µg/mL (lane 2). Blot treated with a secondary IR Dye680-conjugated Goat polyclonal anti-Rabbit antibody was used at a dilution of 1:10000.
产品信息
PA5-19680
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide conjugated to KLH derived from within residues 350 to the C-terminus of Mouse Ihh.
偶联物
形式
Liquid
浓度
0.6 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with BSA
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_10986037
产品详细信息
Heat mediated antigen retrieval recommended prior to tissue staining.
This antibody is predicted to react with cow based on sequence homology.
靶标信息
Ihh encodes a member of the hedgehog family of secreted signaling molecules. Hedgehog proteins are essential regulators of a variety of developmental processes including growth, patterning and morphogenesis. The encoded protein specifically plays a role in bone growth an differentiation. Mutations in this gene are the cause of brachydactyly type A1 which is characterized by shortening or malformation of the phalanges. Mutations in this gene are also the cause of acrocapitofemoral dysplasia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HHG-2; IHH; Indian hedgehog homolog; Indian hedgehog protein; Indian hedgehog protein N-product
基因别名: BDA1; HHG2; IHH
UniProt ID: (Human) Q14623, (Mouse) P97812
Entrez Gene ID: (Human) 3549, (Mouse) 16147
skeletal system development
ossification
patterning of blood vessels
osteoblast differentiation
in utero embryonic development
cell fate specification
morphogenesis of a branching structure
vasculature development
heart looping
positive regulation of mesenchymal cell proliferation
epithelial cell morphogenesis
retinal pigment epithelium development
proteoglycan metabolic process
proteolysis
cell communication
smoothened signaling pathway
cell-cell signaling
multicellular organism development
pattern specification process
positive regulation of cell proliferation
embryo development
embryonic pattern specification
negative regulation of signal transduction
intein-mediated protein splicing
cell differentiation
vitelline membrane formation
pancreas development
positive regulation of chondrocyte differentiation
positive regulation of collagen biosynthetic process
negative regulation of T cell differentiation in thymus
negative regulation of immature T cell proliferation in thymus
positive regulation of T cell differentiation in thymus
multicellular organism growth
chondrocyte proliferation
regulation of growth
embryonic digit morphogenesis
camera-type eye development
negative regulation of apoptotic process
bone resorption
regulation of cell differentiation
negative regulation of cell differentiation
positive regulation of smoothened signaling pathway
positive regulation of transcription from RNA polymerase II promoter
positive regulation of alpha-beta T cell differentiation
negative regulation of alpha-beta T cell differentiation
negative regulation of eye pigmentation
cell maturation
embryonic digestive tract morphogenesis
embryonic camera-type eye morphogenesis
neuron development
smooth muscle tissue development
positive regulation of epithelial cell proliferation
cartilage development
camera-type eye photoreceptor cell fate commitment
head morphogenesis
somite development
embryonic skeletal joint development
epithelial cell-cell adhesion
response to estradiol
maternal process involved in female pregnancy
