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Sequence of this protein is as follows: ESGARVALSA VRPGDRVLAM GEDGSPTFSD VLIFLDREPH RLRAFQVIET QDPPRRLALT PAHLLFTADN HTEPAARFRA TFASHVQPGQ YVLVAGVPG
Ihh encodes a member of the hedgehog family of secreted signaling molecules. Hedgehog proteins are essential regulators of a variety of developmental processes including growth, patterning and morphogenesis. The encoded protein specifically plays a role in bone growth an differentiation. Mutations in this gene are the cause of brachydactyly type A1 which is characterized by shortening or malformation of the phalanges. Mutations in this gene are also the cause of acrocapitofemoral dysplasia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HHG-2; IHH; Indian hedgehog homolog; Indian hedgehog protein
基因别名: BDA1; HHG2; IHH
UniProt ID: (Human) Q14623
Entrez Gene ID: (Human) 3549