Invitrogen

IL-10 Monoclonal Antibody (945A4C437B1)

产品信息

ASC0104

应用

建议稀释比

已发表文章

流式细胞分析 (Flow)

查看1篇已发表文章 1篇已发表文章

酶联免疫吸附实验 (ELISA)

Assay-dependent

查看2篇已发表文章 2篇已发表文章

中和实验 (Neu)

查看1篇已发表文章 1篇已发表文章

Luminex (LUM)

查看1篇已发表文章 1篇已发表文章

亲和纯化 (AP)

查看1篇已发表文章 1篇已发表文章

其他PubMed (Misc)

查看2篇已发表文章 2篇已发表文章

产品规格

已发表种属

Hamster, Pig, Rat

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

945A4C437B1

抗原

Recombinant swine IL-10.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_2536419

靶标信息

IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

A Porcine Model of Zika Virus Infection to Profile the In Utero Interferon Alpha Response.

Methods in molecular biology (Clifton, N.J.)

Trus I,Walker S,Fuchs M,Udenze D,Gerdts V,Karniychuk U

ASC0104 was used in Biosensors to demonstrate altered IFN-α responses in porcine offspring affected with subclinical in utero ZIKV infection.

Wed Mar 10 00:00:00 UTC 2021

A novel DNA vaccine for reduction of PRRSV-induced negative immunomodulatory effects: A proof of concept.

Vaccine

Suradhat S,Wongyanin P,Kesdangsakonwut S,Teankum K,Lumyai M,Triyarach S,Thanawongnuwech R

ASC0104 was used in immunocytochemistry to discuss the role of nucleocapsid-induced IL-10 production and generation of PRRSV-specific Tregs.

Fri Jul 31 00:00:00 UTC 2015

Oral antigen exposure in newborn piglets circumvents induction of oral tolerance in response to intraperitoneal vaccination in later life.

BMC veterinary research

Pasternak JA,Ng SH,Buchanan RM,Mertins S,Mutwiri GK,Gerdts V,Wilson HL

ASC0104 was used in a Luminex assay to investigate whether oral antigen exposure in newborn piglets circumvents induction of oral tolerance in response to intraperitoneal vaccination in later life.

Sat Mar 07 00:00:00 UTC 2015

Cytokine profiles in pregnant gilts experimentally infected with porcine reproductive and respiratory syndrome virus and relationships with viral load and fetal outcome.

Veterinary research

Ladinig A,Lunney JK,Souza CJ,Ashley C,Plastow G,Harding JC

ASC0104 was used in ELISA to compare host cytokine responses between porcine reproductive and respiratory syndrome virus-infected and non-infected pregnant gilts.

Sat Dec 06 00:00:00 UTC 2014

Negative impact of porcine reproductive and respiratory syndrome virus infection on the efficacy of classical swine fever vaccine.

Vaccine

Suradhat S,Kesdangsakonwut S,Sada W,Buranapraditkun S,Wongsawang S,Thanawongnuwech R

ASC0104 was used in flow cytometry to examine the effect of porcine reproductive and respiratory syndrome virus infection on classical swine fever vaccine efficacy.

Fri Mar 24 00:00:00 UTC 2006

Effects of porcine reproductive and respiratory syndrome virus-infected antigen-presenting cells on T cell activation and antiviral cytokine production.

Viral immunology

Charerntantanakul W,Platt R,Roth JA

ASC0104 was used in blocking or activating experiment to show that porcine reproductive and respiratory syndrome virus can suppress T cells

Wed Feb 28 00:00:00 UTC 2007

Immune response characteristics following emergency vaccination of pigs against foot-and-mouth disease.

Vaccine

Barnard AL,Arriens A,Cox S,Barnett P,Kristensen B,Summerfield A,McCullough KC

Tue Jan 11 00:00:00 UTC 2005

Immune response characteristics following emergency vaccination of pigs against foot-and-mouth disease.

Vaccine

Barnard AL,Arriens A,Cox S,Barnett P,Kristensen B,Summerfield A,McCullough KC

Tue Jan 11 00:00:00 UTC 2005

Immune response characteristics following emergency vaccination of pigs against foot-and-mouth disease.

Vaccine

Barnard AL,Arriens A,Cox S,Barnett P,Kristensen B,Summerfield A,McCullough KC

Tue Jan 11 00:00:00 UTC 2005

The kinetics of cytokine production and CD25 expression by porcine lymphocyte subpopulations following exposure to classical swine fever virus (CSFV).

Veterinary immunology and immunopathology

Suradhat S,Sada W,Buranapraditkun S,Damrongwatanapokin S

ASC0104 was used in flow cytometry to report the kinetics of IFN-gamma and interleukin-10 production relative to CD25 expression in porcine lymphocyte subpopulations after immunization with a classical swine fever vaccine

Fri Jul 15 00:00:00 UTC 2005

IL-10 Monoclonal Antibody (945A4C437B1)

产品信息

ASC0104

流式细胞分析 (Flow)

酶联免疫吸附实验 (ELISA)

中和实验 (Neu)

Luminex (LUM)

亲和纯化 (AP)

其他PubMed (Misc)

已发表种属

宿主/亚型

分类

类型

克隆号

抗原

偶联物

形式

浓度

保存条件

运输条件

RRID

靶标信息

性能保障

随时为您服务

Your items have has been added!