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产品信息
M161B
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
14.1
抗原
Recombinant human IL-16
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein G
保存液
PBS with 4% BSA
内含物
proprietary preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_223558
产品详细信息
M161B targets IL-16 in ELISA, and WB applications and shows reactivity with Human samples.
The M161B immunogen is recombinant human IL-16.
M161B detects IL-16 which has a predicted molecular weight of approximately 142 kDa.
The M161B IL16 antibody (biotinylated conjugate of clone 14.1) has successfully been paired as the detection antibody in a sandwich ELISA with capture antibody M160E (clone 17.1) Typical dilutions for sandwich ELISA include 1 µg/mL for coating and 0.125 - 0.25 µg/mL for detection.
Biotinylated antibody M161B (clone 14.1) and antibody M160E (clone 17.1) have successfully been used in combination with recombinant IL16 protein SIL16 in ELISA applications.
靶标信息
The protein encoded by IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of IL-16 undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ16806; FLJ42735; FLJ44234; H-IL-16; il 16; IL-16; ILN; Interleukin; Interleukin-16; Interleukin16; LCF; Lymphocyte chemoattractant factor; M-IL-16; neuronal interleukin 16; Pro-interleukin-16; prointerleukin 16
基因别名: IL16; LCF; NIL16; prIL-16; PRIL16
UniProt ID: (Human) Q14005
Entrez Gene ID: (Human) 3603
