Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
M160E
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Not Applicable
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
17.1
抗原
Recombinant human IL-16
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_223467
产品详细信息
M160E targets IL-16 in ELISA, and WB applications and shows reactivity with Human samples.
The M160E immunogen is recombinant human IL-16.
M160E detects IL-16 which has a predicted molecular weight of approximately 142 kDa.
The M160E IL16 antibody (clone 17.1) has successfully been paired as the coating antibody in a sandwich ELISA with detection antibody M161B (biotinylated conjugate of clone 14.1) Typical dilutions for sandwich ELISA include 1 µg/mL for coating and 0.125 - 0.25 µg/mL for detection.
Antibody M160E (clone 17.1) and biotinylated antibody M161B (clone 14.1) have successfully been used in combination with recombinant IL16 protein SIL16 in ELISA applications.
靶标信息
The protein encoded by IL-16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of IL-16 undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: FLJ16806; FLJ42735; FLJ44234; H-IL-16; il 16; IL-16; ILN; Interleukin; Interleukin-16; Interleukin16; LCF; Lymphocyte chemoattractant factor; M-IL-16; neuronal interleukin 16; Pro-interleukin-16; prointerleukin 16
基因别名: IL16; LCF; NIL16; prIL-16; PRIL16
UniProt ID: (Human) Q14005
Entrez Gene ID: (Human) 3603
