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Description: This monoclonal RN28 antibody reacts with IL-28 (IFN lambda), a member of the IFN-lambda family which mediates the induction of anti-viral protection in a wide variety of cells.
Applications Reported: The RN28 antibody has been reported for use in ELISA capture of mouse IL-28.
Applications Tested: This RN28 antibody has been tested as the capture antibody in a sandwich ELISA for analysis of mouse IL-28 in combination with the biotin polyclonal (Product # 13-7282-81) antibody for detection. A suitable range of concentrations of this antibody for ELISA capture is 1.0-4 µg/mL. A standard curve consisting of doubling dilutions of the recombinant standard over the range of 4000 pg/mL - 30 pg/mL should be included in each ELISA plate.
Purity: Greater than 90%, as determined by SDS-PAGE.
Aggregation: Less than 10%, as determined by HPLC.
Filtration: 0.2 µm post-manufacturing filtered.
IL28 is a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: IFN lambda2; IFN-lambda-2; IFN-lambda-3; IFN-lambda2; IL 28; IL 28 A; IL-28A; IL-28B; ILN; interferon alpha; Interferon lambda-2; Interferon lambda-3; Interferon lambda2; interferon-lambda2; Interleukin; interleukin 28; interleukin 28A; interleukin 28B; Interleukin-28A; Interleukin-28B
基因别名: EG330496; IFL-1; Ifnl2; Ifnl3; IL-28A; IL-28B; Il28; Il28a; Il28b; INF-alpha; INF-lambda
UniProt ID: (Mouse) Q4VK74, (Mouse) Q8CGK6
Entrez Gene ID: (Mouse) 330496, (Mouse) 338374