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This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Mouse IL-28B/IFN-lambda-3.
IL-28B encodes a cytokine distantly related to type I interferons and the IL-10 family. IL-28B, interleukin 28A (IL28A), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: IFN-lambda 3; IFN-lambda-3; IL-28B; ILN; interferon alpha; Interferon lambda-3; Interferon lambda-4; Interleukin; interleukin 28; interleukin 28B; interleukin 28C; Interleukin-28B
基因别名: IFL-1; Ifnl3; IL-28B; Il28; Il28b; INF-alpha; INF-lambda
UniProt ID: (Mouse) Q8CGK6
Entrez Gene ID: (Mouse) 338374