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IL-6 Antibody (PP690) in IHC (F)
Frontiers in endocrinology 2013 -
Figure 5 IL-6 and IL-8 expression in the spleen of a dolphin with hyperinsulinemia . Dolphin splenic tissue sections were incubated with primary anti-porcine IL-6 or anti-dolphin IL-8, followed by anti-dolphin CD2, and nuclear staining using VECTASHIELD mounting medium with DAPI. Original magnification 20x.
产品信息
PP690
应用
建议稀释比
已发表文章
产品规格
种属反应
Pig
已发表种属
Pig
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant porcine IL-6
偶联物
形式
Liquid
浓度
1.0 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_223541
产品详细信息
PP690 targets IL-6 in WB applications and shows reactivity with Porcine samples.
The PP690 immunogen is recombinant porcine IL-6.
PP690 detects IL-6 which has a predicted molecular weight of approximately 21 kDa.
This product is a Low Endotoxin formulation.
This product has been tested for endotoxins by limulus amoebocyte lysate (LAL) assay and contains an endotoxin concentration of less than or equal to 10 endotoxin units per milligram (EU/mg).
靶标信息
IL-6 is a gene that encodes a cytokine that plays a role in inflammation and the maturation of B cells. The protein produced by this gene is an endogenous pyrogen that can induce fever in people with autoimmune diseases or infections. The gene is primarily expressed at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Elevated levels of the encoded protein have been found in virus infections, including COVID-19 (disease caused by SARS-CoV-2). Diseases associated with IL6 include Kaposi Sarcoma and Rheumatoid Arthritis, Systemic Juvenile.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: H-IL-6; IL-6; ILN; Interleukin; Interleukin-6; interleukin-6 protein; Interleukin6; M-IL-6; R-IL-6
基因别名: IL6
UniProt ID: (Pig) P26893
Entrez Gene ID: (Pig) 399500
