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IL17RB Antibody (PA5-85497) in WB
Western Blot using IL17RB Polyclonal Antibody (Product # PA5-85497). Non-transfected (–) and transfected (+) 293T whole cell extracts (30 µg) were separated by 10% SDS-PAGE, and the membrane was blotted with IL17B Receptor antibody IL17RB Polyclonal Antibody (Product # PA5-85497) diluted at 1:1,000.
产品信息
PA5-85497
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to human IL17B Receptor.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2792637
产品详细信息
Keep as concentrated solution.
Positive Control: human IL17RB-transfected MCF-10A cells, IL17BR -transfected 293T cells.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are termed as IL-17B, IL-17C (1) and IL-17E. IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL-17B, C, and E like IL-17 are able to induce proinflammatory responses. However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist. Receptor for IL-17B and IL-17E has been independently isolated and has been designated as EV127 (in mouse) and IL-17Rh1 (in human), respectively. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8. IL-17Rh1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cytokine receptor CRL4; Cytokine receptor-like 4; IL-17 receptor B; IL-17 receptor homolog 1; IL-17B; IL-17B receptor; IL-17RB; IL-17Rh1; IL-20; interleukin 17 receptor homolog 1; interleukin 17B receptor; Interleukin-17 receptor B; Interleukin-17B receptor; MGC138900; MGC138901; MGC5245; ZCYTO7
基因别名: CRL4; EVI27; IL17BR; IL17RB; IL17RH1; UNQ2501/PRO19612
UniProt ID: (Human) Q9NRM6
Entrez Gene ID: (Human) 55540
