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产品信息
PA5-34499
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A 16 amino acid peptide near the center of human IL-17RE
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2551851
产品详细信息
A suggested positive control is human ovary tissue lysate.
PA5-34499 can be used with blocking peptide PEP-1542.
靶标信息
The interleukin 17 receptor E (IL-17RE) shares limited similarity to the receptor of IL-17A, a ubiquitous type I membrane glycoprotein that with IL-17A plays a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. IL-17RE is the functional receptor of IL-17C and has been suggested to mediate mucosal immunity to infection with intestinal pathogens. IL-17C is produced by epithelia in response to bacterial challenge and binds to a receptor complex formed by IL-17RE and IL-17RA on the epithelial cell surface, thereby regulating the immune function of epithelial cells in an autocrine manner.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: IL-17 receptor E; IL-17RE; Interleukin-17 receptor E
基因别名: AA589509; IL-17RE; IL17RE; Il25r; UNQ3056/PRO9877
UniProt ID: (Human) Q8NFR9, (Mouse) Q8BH06, (Rat) Q6AZ51
Entrez Gene ID: (Human) 132014, (Mouse) 57890, (Rat) 362417
