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IL17RE Antibody (PA5-89747) in WB
Western blot analysis of IL17RE in extracts of various cell lines. Samples were incubated with IL17RE Polyclonal antibody (Product # PA5-89747) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
产品信息
PA5-89747
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 24-260 of human IL17RE (NP_7056131)
偶联物
形式
Liquid
浓度
1.98 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805756
产品详细信息
Immunogen sequence: AGIGFRHLPH WNTRCPLASH TDDSFTGSSA YIPCRTWWAL FSTKPWCVRV WHCSRCLCQH LLSGGSGLQR GLFHLLVQKS KKSSTFKFYR RHKMPAPAQR KLLPRRHLSE KSHHISIPSP DISHKGLRSK RTQPSDPETW ESLPRLDSQR HGGPEFSFDL LPEARAIRVT ISSGPEVSVR LCHQWALECE ELSSPYDVQK IVSGGHTVEL PYEFLLPCLC IEASYLQEDT VRRKKCP; Positive Samples: HT-29, A-549, A-431, Mouse kidney, Mouse thymus; Cellular Location: Cell membrane, Cytoplasm, Single-pass type I membrane protein
靶标信息
The interleukin 17 receptor E (IL-17RE) shares limited similarity to the receptor of IL-17A, a ubiquitous type I membrane glycoprotein that with IL-17A plays a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. IL-17RE is the functional receptor of IL-17C and has been suggested to mediate mucosal immunity to infection with intestinal pathogens. IL-17C is produced by epithelia in response to bacterial challenge and binds to a receptor complex formed by IL-17RE and IL-17RA on the epithelial cell surface, thereby regulating the immune function of epithelial cells in an autocrine manner.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: IL-17 receptor E; Interleukin-17 receptor E
基因别名: AA589509; IL-17RE; IL17RE; Il25r; UNQ3056/PRO9877
UniProt ID: (Human) Q8NFR9, (Mouse) Q8BH06
Entrez Gene ID: (Human) 132014, (Mouse) 57890
