Invitrogen

IL1R1 Polyclonal Antibody

IL1R1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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IL1R1 Antibody (PA5-97866) in IHC (P)

Immunohistochemical analysis of IL1R1 in paraffin embedded human placenta tissue using a IL1R1 polyclonal antibody (Product # PA5-97866) at a dilution of 1:100.

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产品信息

PA5-97866

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

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免疫组化 (IHC)

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免疫组化（石蜡） (IHC (P))

1:20-1:200

酶联免疫吸附实验 (ELISA)

Assay-Dependent

免疫沉淀 (IP)

- -

产品规格

种属反应

Human, Mouse

已发表种属

Human, Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant Human Interleukin-1 receptor type 1 protein (31-80AA)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C or -80°C if preferred

运输条件

Wet ice

AB_2812480

靶标信息

The IL-1 system includes two agonists (IL-1 and IL-1), converting enzymes, antagonists, two receptors (IL-1 RI and IL-1 RII) and the IL-1 receptor accessory protein. Interleukin-1 signal is transduced through the type I receptor.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Identification of a neutrophil-specific PIK3R1 mutation facilitates targeted treatment in a patient with Sweet syndrome.

The Journal of clinical investigation

Bhattacharya S,Basu S,Sheng E,Murphy C,Wei J,Kersh AE,Nelson CA,Bryer JS,Ashchyan HA,Steele K,Forrestel A,Seykora JT,Micheletti RG,James WD,Rosenbach M,Leung TH

PA5-97866 was used in ELISA, Immunohistochemistry (Paraffin), Western Blot to allow this method to be generalizable to other inflammatory diseases and demonstrates a potential personalized medicine approach for patients with clinically challenging disease.

Tue Jan 03 00:00:00 UTC 2023

Identification of a neutrophil-specific PIK3R1 mutation facilitates targeted treatment in a patient with Sweet syndrome.

The Journal of clinical investigation

Bhattacharya S,Basu S,Sheng E,Murphy C,Wei J,Kersh AE,Nelson CA,Bryer JS,Ashchyan HA,Steele K,Forrestel A,Seykora JT,Micheletti RG,James WD,Rosenbach M,Leung TH

Tue Jan 03 00:00:00 UTC 2023

IL-1 receptor signaling in podocytes limits susceptibility to glomerular damage.

American journal of physiology. Renal physiology

Ren J,Lu X,Hall G,Privratsky JR,Robson MJ,Blakely RD,Crowley SD

PA5-97866 was used in ELISA, Immunohistochemistry (Paraffin), Western Blot to establish that activation of the receptor for interleukin-1 limits susceptibility to damage to the kidney glomerulus in preclinical mouse models by stimulating Akt signaling cascades inside the podocyte.

Tue Feb 01 00:00:00 UTC 2022

生物信息学

蛋白别名: antigen CD121a; CD121 alpha; CD121 antigen-like family member A; CD121a; il-1 receptor; IL-1 receptor alpha chain; il-1r; IL-1R-1; IL-1R-alpha; IL-1RT-1; IL-1RT1; il1 receptor; interleukin 1 receptor alpha, type I; interleukin 1 receptor, type I; interleukin-1 receptor; Interleukin-1 receptor alpha; Interleukin-1 receptor type 1; Interleukin-1 receptor type I; p80

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基因别名: CD121A; CD121b; D2S1473; IL-1R-alpha; IL-1R1; IL-iR; IL1R; Il1r-1; IL1R1; IL1RA; IL1RT1; P80

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UniProt ID: (Human) P14778, (Mouse) P13504

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Entrez Gene ID: (Human) 3554, (Mouse) 16177

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功能

protease binding signal transducer activity transmembrane signaling receptor activity interleukin-1 receptor activity interleukin-1, Type I, activating receptor activity platelet-derived growth factor receptor binding protein binding ionotropic glutamate receptor binding transmembrane signal receptor

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