Invitrogen

IL20RB Polyclonal Antibody

IL20RB Antibody in Western Blot, Immunocytochemistry, Immunohistochemistry (WB, ICC/IF, IHC)

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IL20RB Antibody (PA5-49927) in WB, ICC/IF, IHC

The Journal of clinical investigation 2022 - Figure 1 IL20RB expression is associated with lung cancer bone metastasis. ( A ) Expression heatmap of upregulated genes in highly (red) versus weakly/mildly (blue) bone-metastatic A549-derivative cell lines. ( B and C ) IL-20RB protein ( B ) and mRNA levels ( C ) in A549-derivative cell lines. ( D - K ) Analysis of IL20RB expression in an SHTCH lung cancer cohort. IL20RB expression in paired normal and can... View More

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产品信息

PA5-49927

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:3,000

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免疫组化 (IHC)

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免疫组化（冰冻） (IHC (F))

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免疫细胞化学 (ICC/IF)

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产品规格

种属反应

Human, Mouse

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthesized peptide derived from internal of human IL20RB.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice

AB_2635380

产品详细信息

The antibody detects endogenous levels of total IL20RB protein.

靶标信息

IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20 (IL20; MIM 605619) (Blumberg et al., 2001 [PubMed 11163236]).[supplied by OMIM, Feb 2009].

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

IL-20RB mediates tumoral response to osteoclastic niches and promotes bone metastasis of lung cancer.

The Journal of clinical investigation

He Y,Luo W,Liu Y,Wang Y,Ma C,Wu Q,Tian P,He D,Jia Z,Lv X,Ma YS,Yang H,Xu K,Zhang X,Xiao Y,Zhang P,Liang Y,Fu D,Yao F,Hu G

PA5-49927 was used in Sample Preparation to reveal a direct pro-tumor role of osteoclastic niche in bone metastasis and supported IL20RB-targeting approaches for metastasis treatment.

Mon Oct 17 00:00:00 UTC 2022

IL-20RB mediates tumoral response to osteoclastic niches and promotes bone metastasis of lung cancer.

The Journal of clinical investigation

He Y,Luo W,Liu Y,Wang Y,Ma C,Wu Q,Tian P,He D,Jia Z,Lv X,Ma YS,Yang H,Xu K,Zhang X,Xiao Y,Zhang P,Liang Y,Fu D,Yao F,Hu G

PA5-49927 was used in Sample Preparation to reveal a direct pro-tumor role of osteoclastic niche in bone metastasis and supported IL20RB-targeting approaches for metastasis treatment.

Mon Oct 17 00:00:00 UTC 2022

IL-20RB mediates tumoral response to osteoclastic niches and promotes bone metastasis of lung cancer.

The Journal of clinical investigation

He Y,Luo W,Liu Y,Wang Y,Ma C,Wu Q,Tian P,He D,Jia Z,Lv X,Ma YS,Yang H,Xu K,Zhang X,Xiao Y,Zhang P,Liang Y,Fu D,Yao F,Hu G

PA5-49927 was used in Sample Preparation to reveal a direct pro-tumor role of osteoclastic niche in bone metastasis and supported IL20RB-targeting approaches for metastasis treatment.

Mon Oct 17 00:00:00 UTC 2022

IL-20RB mediates tumoral response to osteoclastic niches and promotes bone metastasis of lung cancer.

The Journal of clinical investigation

He Y,Luo W,Liu Y,Wang Y,Ma C,Wu Q,Tian P,He D,Jia Z,Lv X,Ma YS,Yang H,Xu K,Zhang X,Xiao Y,Zhang P,Liang Y,Fu D,Yao F,Hu G

PA5-49927 was used in Sample Preparation to reveal a direct pro-tumor role of osteoclastic niche in bone metastasis and supported IL20RB-targeting approaches for metastasis treatment.

Mon Oct 17 00:00:00 UTC 2022

生物信息学

蛋白别名: Fibronectin type III domain containing 6; FNDC6; IL-20 receptor subunit beta; IL-20R-beta; IL-20R2; IL-20RB; interleukin 20 receptor beta subunit; interleukin-20 receptor II; Interleukin-20 receptor subunit beta

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基因别名: AV228068; DIRS1; FNDC6; Gm186; IL-20R2; Il20R2; IL20RB; UNQ557/PRO1114

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UniProt ID: (Human) Q6UXL0

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Entrez Gene ID: (Human) 53833, (Mouse) 213208

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功能

cytokine receptor activity interleukin-20 binding transmembrane signal receptor

参与通路