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IMPDH1 Antibody (PA5-116702) in WB
Western blot analysis of IMPDH1 in extracts of various cell lines. Samples were incubated with IMPDH1 Polyclonal antibody (Product # PA5-116702) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
PA5-116702
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 434-563 of human IMPDH1 (NP_8990661)
偶联物
形式
Liquid
浓度
1.05 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2901333
产品详细信息
Positive Samples: BT-474, HT-29, Mouse pancreas
Immunogen sequence: MMGSLLAATT EAPGEYFFSD GVRLKKYRGM GSLDAMEKSS SSQKRYFSEG DKVKIAQGVS GSIQDKGSIQ KFVPYLIAGI QHGCQDIGAR SLSVLRSMMY SGELKFEKRT MSAQIEGGVH GLHSYEKRLY
靶标信息
The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp781N0678; IMP (inosine 5'-monophosphate) dehydrogenase 1; IMP (inosine monophosphate) dehydrogenase 1; IMP dehydrogenase 1; IMP dehydrogenase 1 {ECO:0000255|HAMAP-Rule:MF_03156}; IMPD 1; IMPD 1 {ECO:0000255|HAMAP-Rule:MF_03156}; IMPDH 1; IMPDH 1 {ECO:0000255|HAMAP-Rule:MF_03156}; IMPDH-I; inosine 5'-phosphate dehydrogenase 1; inosine monophosphate dehydrogenase 1; Inosine-5'-monophosphate dehydrogenase 1; inosine-5'-monophosphate dehydrogenase 1 {ECO:0000255|HAMAP-Rule:MF_03156}
基因别名: B930086D20Rik; IMPD; IMPD 1; IMPD1; IMPDH 1; IMPDH-I; IMPDH1; LCA11; RP10; sWSS2608
UniProt ID: (Human) P20839, (Mouse) P50096
Entrez Gene ID: (Human) 3614, (Rat) 362329, (Mouse) 23917
