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产品信息
PA5-22231
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 699 and 949 of INPP5B (Uniprot ID#P32019)
偶联物
形式
Liquid
浓度
0.34 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11153388
产品详细信息
Recommended positive controls: H1299, HeLa, HepG2, Molt-4, Raji.
Predicted reactivity: Mouse (87%), Rat (87%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). INPP5B encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 5PTase; 75 kDa inositol polyphosphate-5-phosphatase; inositol polyphosphate-5-phosphatase, 75kDa; MGC65156; MGC71303; Phosphoinositide 5-phosphatase; RP11-109P14.7; Type II inositol 1,4,5-trisphosphate 5-phosphatase; type II inositol-1
基因别名: 5PTase; INPP5B; OCRL2
UniProt ID: (Human) P32019
Entrez Gene ID: (Human) 3633
