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INPP5F Antibody (MA5-27229) in IHC (P)
Immunohistochemistry was performed on paraffin-embedded human pancreas tissue. To expose target proteins, heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min. Following antigen retrieval, tissues were probed with a INPP5F monoclonal antibody (Product # MA5-27229) at a dilution of 1:500.
产品信息
MA5-27229
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI1D4
抗原
Full length human recombinant protein of INPP5F produced in HEK293T cell
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2723292
靶标信息
SAC2 is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants have been observed, but most of them are not thought to be protein-coding.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EC 3.1.3.36; hSAC2; Inositol polyphosphate 5-phosphatase F; OCRL 1; Phosphatidylinositide phosphatase SAC2; Sac domain-containing inositol phosphatase 2; Sac domain-containing phosphoinositide 4-phosphatase 2; sac domain-containing phosphoinositide 5-phosphatase 2
基因别名: hSAC2; INPP5F; KIAA0966; MSTP007; MSTP047; MSTPO47; SAC2
UniProt ID: (Human) B3KRF1
Entrez Gene ID: (Human) 22876
protein binding
inositol monophosphate 1-phosphatase activity
phosphatidylinositol phosphate 5-phosphatase activity
phosphatidylinositol phosphate 4-phosphatase activity
protein homodimerization activity
inositol monophosphate 3-phosphatase activity
inositol monophosphate 4-phosphatase activity
phosphatase
positive regulation of receptor recycling
phosphatidylinositol biosynthetic process
cardiac muscle hypertrophy in response to stress
phosphatidylinositol catabolic process
negative regulation of tyrosine phosphorylation of Stat3 protein
phosphatidylinositol dephosphorylation
phosphatidylinositol-mediated signaling
negative regulation of axon regeneration
regulation of protein kinase B signaling
clathrin-mediated endocytosis
regulation of cell motility
regulation of endocytic recycling
