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INSRR Antibody (PA5-14691) in IHC (P)
Immunohistochemistry analysis of INSRR in formalin-fixed and paraffin-embedded human cancer tissue. Samples were incubated with INSRR polyclonal antibody (Product # PA5-14691) which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepa... View More
产品信息
PA5-14691
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 1256-1287 amino acids from the C-terminal region of human Insulin Receptor R
偶联物
形式
Liquid
纯化类型
Size-exclusion - Dialysis, Ammonium sulfate precipitation
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2249190
靶标信息
INSRR, insulin receptor-related receptor, is a member of the insulin receptor (IR) family. INSRR does not bind insulin-like molecules, but is similar to INSR in tyrosine kinase activity. Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH. Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Insulin receptor-related protein; Insulin receptor-related protein alpha chain; Insulin receptor-related protein beta chain; insulin receptor-related receptor; IR-related receptor; IRR
基因别名: INSRR; IRR
UniProt ID: (Human) P14616
Entrez Gene ID: (Human) 3645
