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IQGAP1 Monoclonal Antibody (2C5)

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抗体检测数据 (1)

IQGAP1 Antibody in Western Blot (WB)

IQGAP1 Antibody in Western Blot (WB)

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IQGAP1 Antibody (H00008826-M01) in WB

IQGAP1 monoclonal antibody (M01), clone 2C5. Western Blot analysis of IQGAP1 expression in C32.

IQGAP1 Antibody in Western Blot (WB)

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IQGAP1 Antibody in Western Blot (WB) — IQGAP1 monoclonal antibody (M01), clone 2C5. Western Blot analysis of IQGAP1 expression in C32.

产品信息

H00008826-M01

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1-5 µg/mL

-

免疫组化（石蜡） (IHC (P))

3 µg/mL

-

免疫细胞化学 (ICC/IF)

10-100 µg/mL

-

酶联免疫吸附实验 (ELISA)

10 µg/mL

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

2C5

抗原

IQGAP1 (NP_003861, 611 a.a. approximately 710 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.47 mg/mL

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

no preservative

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Product may be used with Western Blot (Cell lysate).

Immunogen sequence: WQSNKDTQEA QKFALGIFAI NEAVESGDVG KTLSALRSPD VGLYGVIPEC GETYHSDLAE AKKKKLAVGD NNSKWVKHWV KGGYYYYHNL ETQEGGWDEP

靶标信息

This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: DISP2; DISPB; p195; Ras GTPase-activating-like protein IQGAP1; RasGAP-like with IQ motifs

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基因别名: HUMORFA01; IQGAP1; KIAA0051; p195; SAR1

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UniProt ID: (Human) P46940

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Entrez Gene ID: (Human) 8826

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GTPase inhibitor activity GTPase activator activity calcium ion binding protein binding calmodulin binding phosphatidylinositol-3,4,5-trisphosphate binding protein kinase binding protein phosphatase binding protein domain specific binding protein complex binding protein serine/threonine kinase activator activity S100 protein binding Rac GTPase binding cadherin binding involved in cell-cell adhesion G-protein modulator protein-binding activity modulator GTPase-activating protein

regulation of cytokine production signal transduction epidermal growth factor receptor signaling pathway fibroblast growth factor receptor signaling pathway negative regulation of GTPase activity negative regulation of dephosphorylation cellular response to platelet-derived growth factor stimulus positive regulation of GTPase activity positive regulation of protein kinase activity platelet-derived growth factor receptor signaling pathway cellular response to calcium ion cellular response to epidermal growth factor stimulus positive regulation of protein serine/threonine kinase activity glomerular visceral epithelial cell development cell-cell adhesion neuron projection extension