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ISG20 Antibody (PA5-120291) in WB
Western blot analysis of ISG20 in extracts of various cell lines. Samples were incubated with ISG20 Polyclonal antibody (Product # PA5-120291) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
PA5-120291
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human ISG20 (NP_002192.2).
偶联物
形式
Liquid
浓度
0.91 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2913863
产品详细信息
Positive test controls include: Raji, A-549, MCF7, Mouse spleen, Rat spleen. The target is usually found in the following locations: Cajal body, Cytoplasm, Nucleus, nucleolus.
Immunogen sequence: MAGSREVVAM DCEMVGLGPH RESGLARCSL VNVHGAVLYD KFIRPEGEIT DYRTRVSGVT PQHMVGATPF
靶标信息
Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single-stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis. [UniProt]
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Estrogen-regulated transcript 45 protein; interferon stimulated exonuclease; interferon stimulated exonuclease 20; interferon stimulated exonuclease gene 20kDa; interferon stimulated gene 20kDa; Interferon-stimulated gene 20 kDa protein; interferon-stimulated protein; Promyelocytic leukemia nuclear body-associated protein ISG20; Protein DnaQL
基因别名: 1600023I01Rik; 2010107M23Rik; 20kDa; CD25; DnaQL; HEM45; ISG20
UniProt ID: (Human) Q96AZ6, (Mouse) Q9JL16
Entrez Gene ID: (Human) 3669, (Mouse) 57444, (Rat) 293052
DNA catabolic process, exonucleolytic
rRNA processing
RNA catabolic process
cell proliferation
response to virus
negative regulation of viral genome replication
defense response to virus
type I interferon signaling pathway
RNA phosphodiester bond hydrolysis, exonucleolytic
immune system process
innate immune response
nucleic acid phosphodiester bond hydrolysis
