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产品信息
PA5-46025
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the N-terminal of human IST1 (aa 19-68).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2608540
产品详细信息
Peptide sequence: INRLKLLEKK KTELAQKARK EIADYLAAGK DERARIRVEH IIREDYLVEA
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
靶标信息
Proposed to be involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Charged multivesicular body protein 8; CHMP8; hIST1; increased sodium tolerance 1 homolog; IST1 homolog; IST1, endosomal sorting complex required for transport-III component; MGC117220; overexpressed in lung cancer 1; pm28; Putative MAPK-activating protein PM28
基因别名: IST1; KIAA0174; OLC1
UniProt ID: (Human) P53990
Entrez Gene ID: (Human) 9798
cytokinesis
positive regulation of defense response to virus by host
protein localization
abscission
protein transport
viral release from host cell
multivesicular body assembly
establishment of protein localization
positive regulation of proteolysis
viral capsid secondary envelopment
positive regulation of collateral sprouting
cell division
cell-cell adhesion
mitophagy in response to mitochondrial depolarization
xenophagy
ESCRT III complex disassembly
