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Immunogen sequence: APRLQSEVAE LKIVADQLCA KYSKEYGKLC RTNQIGTVND RLMHKLSVEA PPKILVERYL IEIAKNYNVP YEPDSVVMAE APPGVETDLI DVGFTDD
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
Proposed to be involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Charged multivesicular body protein 8; CHMP8; hIST1; increased sodium tolerance 1 homolog; IST1 homolog; IST1, endosomal sorting complex required for transport-III component; MGC117220; overexpressed in lung cancer 1; pm28; Putative MAPK-activating protein PM28
基因别名: IST1; KIAA0174; OLC1
UniProt ID: (Human) P53990
Entrez Gene ID: (Human) 9798