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Invitrogen
Interferon alpha-4/10/14 Polyclonal Antibody
FIGURE: 1 / 4
Interferon alpha-4/10/14 Antibody (PA5-100829) in ICC/IF
Immunocytochemistry analysis of Interferon alpha-4/10/14 in Hela cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with Interferon alpha-4/10/14 polyclonal antibody (Product # PA5-100829) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an A... View More
Product Details
PA5-100829
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human IFNA4/10/14, corresponding to a region within C-terminal amino acids.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2850330
Product Specific Information
Antibody detects endogenous levels of total IFNA4/10/14.
Target Information
IFNA4 (Interferon Alpha 4) and IFNA14 (Interferon Alpha 14) are predicted to enable cytokine activity and type I interferon receptor binding activity and to be involved in several processes, including B cell activation; lymphocyte activation involved in immune response; and positive regulation of peptidyl-serine phosphorylation of STAT protein. IFNA10 (Interferon Alpha 10) encodes a protein that belongs to the type I interferon family of proteins, and is located in a cluster of alpha interferon genes on chromosome 9. Interferons are small regulatory molecules that function in cell signaling in response to viruses and other pathogens or tumor cells. This gene is intronless and the encoded protein is secreted.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: IFN-alpha-10; IFN-alpha-14; IFN-alpha-4; Interferon; interferon alpha 14; interferon alpha family, gene 4; Interferon alpha-10; Interferon alpha-14; Interferon alpha-4; Interferon alpha-4B; Interferon alpha-6L; Interferon alpha-76; Interferon alpha-C; Interferon alpha-H; Interferon alpha-M1; Interferon lambda-2-H; interferon, alpha 10; interferon, alpha 14; interferon, alpha 4; LeIF C; LeIF H; MuIFN-alpha 4
Gene Aliases: Ifa4; IFN-alpha4a; IFN-alphaC; IFN-alphaH; IFNA10; IFNA14; IFNA4; INFA4; LEIF2H; OTTMUSG00000007662
UniProt ID: (Human) P01566, (Human) P01570, (Human) P05014, (Mouse) P07351
Entrez Gene ID: (Human) 3446, (Human) 3448, (Human) 3441, (Mouse) 404549, (Mouse) 15967
adaptive immune response
T cell activation involved in immune response
natural killer cell activation involved in immune response
humoral immune response
blood coagulation
cytokine-mediated signaling pathway
B cell differentiation
positive regulation of peptidyl-serine phosphorylation of STAT protein
B cell proliferation
response to exogenous dsRNA
innate immune response
defense response to virus
type I interferon signaling pathway
regulation of type I interferon-mediated signaling pathway
response to virus
defense response
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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