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J Chain Antibody (MA1-80527) in WB
Plant biotechnology journal 2019 -
Figure 3 Western blot characterization of the selected transformants for each transformation strategy. Detection of SC (a and d), J-chain (b and e) and VHH -IgA (c and f) in a western blot after reducing (+) and non-reducing (-) PAGE . The main bands, indicated with a number, most likely correspond with SC in different glycosylated forms (1), a postulated dimeric SC (2), the assembled sSIgA complex (3), J-c... View More
产品信息
MA1-80527
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Human,
Pig
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
Mc19-9
抗原
Human J Chain.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
TBS
内含物
<0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_934333
产品详细信息
This antibody does not detect J chain in intact IgM in ELISA Assays due to steric hindrance. In Western Blotting techniques MA1-80527 detects J chain in IgM only under reducing conditions.
Mouse anti Human J chain antibody, clone Mc19-9 reacts with human J chain as tested by ELISA using purified human Ig fragments as the solid phase target antigen.
靶标信息
J chain is a small glycopeptide and is structurally unrelated to heavy or light chains, but is synthesized by all plasma cells that secrete polymeric immunoglobulins. J chain is linked to IgA and IgM by disulfide bonds, however, it has been detected in IgG- and IgD-containing cells. J chains are present in a large proportion of the immunoglobulin-positive cells in the germinal centers of the tonsil and lymph node. B cells secrete J chain at an early stage of differentiation with the expression persisting in those cells destined to produce IgA or IgM.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: IgJ chain; Immunoglobulin J chain; immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides; J chain; Joining chain of multimeric IgA and IgM
基因别名: IGCJ; IGJ; JCH; JCHAIN
UniProt ID: (Human) P01591
Entrez Gene ID: (Human) 3512
