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产品信息
PA5-60756
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2642842
产品详细信息
Immunogen sequence: LVEKNKRMNK KNEDLLQSIQ RMEEKIKNLT RENVEMKEKL SAQASLKRHT SLNDLSLTRD EQEIEFLRLQ VLEQQHVIDD LSL
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 96%.
靶标信息
JAKMIP1, also known as Marlin-1, is a highly-conserved vertebrate-specific microtubule-associated protein that plays a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements. JAKMIP1 is expressed predominantly in neuronal and lymphoid cells and colocalizes with microtubules. Multiple isoforms of JAKMIP1 are known to exist: isoforms 1 and 5 are also expressed in liver, lung and skeletal muscle, while isoforms 2-4 are specifically expressed in brain and retina. JAKMIP1 participates in polarized secretion in lymphocytes and it has been suggested to be a novel effector memory gene restraining T cell-mediated cytotoxicity. Dysregulation of JAKMIP1 gene expression is associated with genetic conditions linked to autism in humans.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ31564; GABA-B receptor-binding protein; Jak and microtubule interacting protein 1; Janus kinase and microtubule-interacting protein 1; Marlin-1; Multiple alpha-helices and RNA-linker protein 1; multiple coiled-coil GABABR1-binding protein
基因别名: GABABRBP; JAKMIP1; JAMIP1; MARLIN1
UniProt ID: (Human) Q96N16
Entrez Gene ID: (Human) 152789
