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Positive test controls include: HeLa, Jurkat, HepG2, Rat testis. The target is usually found in the following locations: Nucleus.
Immunogen sequence: MVAGWPATPP AMMPGQIPDP SVTTGSLPGL GPLTGLPSSA LTVEELKYAD IRNLGAMIAP LHFLEVKLGK RPQPVKSELD EEEERRKRRR EKNKVAAARC RNKKKERTEF LQRESERLEL MNAELKTQIE ELKQERQQLI LMLNRHRPTC IVRTDSVKTP ESEGNPLLEQ LEKK
Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Jun dimerization protein 2; progesterone receptor co-activator
基因别名: Jdp-2; JDP2; JUNDM2; Jundp2
UniProt ID: (Human) Q8WYK2, (Rat) Q78E65
Entrez Gene ID: (Human) 122953, (Rat) 116674