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JLP Antibody (A300-336A) in IHC (P)
Detection of human JLP by immunohistochemistry. Sample: FFPE section of human seminoma. Antibody: Affinity purified rabbit anti-JLP antibody (Product # A300-336A) (Lot 4) used at 1:1000 (1 µg/mL). Secondary: HRP-conjugated goat anti-rabbit IgG (A120-501P). Detection: DAB.
产品信息
A300-336A
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 1 and 50 of human JNK/SAPK-Associated Protein.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
phosphate/tris citrate, pH 7-8
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
靶标信息
This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain, and a cytoplasmic region. This protein acts as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome as well as non-syndromic cleft lip with or without cleft palate. Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: c-Jun NH2-terminal kinase-associated leucine zipper protein; C-Jun-amino-terminal kinase-interacting protein 4; Cancer/testis antigen 89; CT89; HLC-6; Human lung cancer oncogene 6 protein; JIP-4; JLP; JNK interacting protein; JNK-associated leucine-zipper protein; JNK-interacting leucine zipper; JNK-interacting protein 4; JNK/SAPK-associated protein; JNK/SAPK-associated protein 2; JSAP2; lung cancer oncogene 4; Max-binding protein; Mitogen-activated protein kinase 8-interacting protein 4; PHET; proliferation-inducing gene 6; Proliferation-inducing protein 6; Protein highly expressed in testis; sperm associated antigen 9 variant 5; Sperm surface protein; Sperm-associated antigen 9; Sperm-specific protein; Sunday driver 1
基因别名: 3110018C07Rik; 4733401I23Rik; 4831406C20Rik; AW552012; CT89; HLC-6; HLC4; HLC6; HSS; JIP-4; JIP4; JLP; JSAP2; JSAP2a; KIAA0516; MAPK8IP4; PHET; PIG6; SPAG9; SYD1
UniProt ID: (Human) O60271, (Mouse) Q58A65
Entrez Gene ID: (Human) 9043, (Mouse) 70834
activation of JUN kinase activity
spermatogenesis
positive regulation of cell migration
retrograde transport, endosome to Golgi
positive regulation of neuron differentiation
striated muscle cell differentiation
positive regulation of muscle cell differentiation
protein homooligomerization
negative regulation of protein homodimerization activity
activation of MAPK activity
positive regulation of signal transduction
vesicle-mediated transport
positive regulation of MAPK cascade
