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JMJD1B Antibody (MA5-45972) in ICC/IF
Immunofluorescence analysis of JMJD1B was performed using 70% confluent log phase HCT 116 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with JMJD1B Recombinant Rabbit Monoclonal Antibody (PSH0-11) (Product # MA5-45972) at 1:100 dilution in 0.1% BSA, incubated at 4 degree celsius overnight and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Recombinant Secondary Antibod... View More
产品信息
MA5-45972
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
PSH0-11
抗原
Recombinant protein within human KDM3B aa 251-500.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS with 0.1% BSA, 40% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2937393
产品详细信息
Predicted band size: 191 kDa
Positive Control: Hela cell lysate, NIH/3T3 cell lysate, Hela.
Subcellular Location: Nucleus.
Sequence Similarities: 92.96% Mouse; 90.14% Rat.
Tissue Specificity: Ubiquitous. Highly expressed in placenta, skeletal muscle, kidney, heart and liver.
靶标信息
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: [histone H3]-dimethyl-L-lysine(9) demethylase 3B; JmjC domain-containing histone demethylation protein 2B; jumonji domain containing 1B; Jumonji domain-containing protein 1B; lysine (K)-specific demethylase 3B; Lysine-specific demethylase 3B; Nuclear protein 5qNCA
基因别名: 5830462I21Rik; 5qNCA; C5orf7; JHDM2B; JMJD1B; KDM3B; KIAA1082; mKIAA1082; NET22
UniProt ID: (Human) Q7LBC6, (Mouse) Q6ZPY7
Entrez Gene ID: (Human) 51780, (Mouse) 277250
antioxidant activity
histone demethylase activity
metal ion binding
dioxygenase activity
sulfonate dioxygenase activity
molecular_function
oxidoreductase activity
2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity
procollagen-proline dioxygenase activity
hypophosphite dioxygenase activity
DNA-N1-methyladenine dioxygenase activity
C-19 gibberellin 2-beta-dioxygenase activity
C-20 gibberellin 2-beta-dioxygenase activity
histone modifying enzyme
