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Product Details
PA5-22132
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 234 (Q6NYC1) of PSR
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_11156206
Product Specific Information
Recommended positive controls: 293T, NIH-3T3.
Predicted reactivity: Mouse (98%), Rat (98%), Zebrafish (87%), Xenopus laevis (87%), Chicken (96%), Chimpanzee (100%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: apoptotic cell clearance receptor PtdSerR; Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; Histone arginine demethylase JMJD6; JmjC domain-containing protein 6; jumonji domain containing 6; Jumonji domain-containing protein 6; Lysyl-hydroxylase JMJD6; Peptide-lysine 5-dioxygenase JMJD6; Phosphatidylserine receptor; Protein PTDSR
Gene Aliases: 5730436I23Rik; D11Ertd195e; JMJD6; KIAA0585; mKIAA0585; PSR; PtdSerR; PTDSR; PTDSR1
UniProt ID: (Human) Q6NYC1, (Mouse) Q9ERI5
Entrez Gene ID: (Human) 23210, (Mouse) 107817
RNA binding
single-stranded RNA binding
receptor activity
iron ion binding
protein binding
histone demethylase activity
histone demethylase activity (H3-R2 specific)
histone demethylase activity (H4-R3 specific)
identical protein binding
protein homodimerization activity
peptidyl-lysine 5-dioxygenase activity
sulfonate dioxygenase activity
oxidoreductase activity
2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity
procollagen-proline dioxygenase activity
hypophosphite dioxygenase activity
DNA-N1-methyladenine dioxygenase activity
metal ion binding
dioxygenase activity
C-19 gibberellin 2-beta-dioxygenase activity
C-20 gibberellin 2-beta-dioxygenase activity
protein modifying enzyme
kidney development
sprouting angiogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
mRNA processing
cell surface receptor signaling pathway
heart development
RNA splicing
peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine
lung development
T cell differentiation in thymus
macrophage activation
recognition of apoptotic cell
regulation of mRNA splicing, via spliceosome
erythrocyte development
oxidation-reduction process
retina development in camera-type eye
histone H3-R2 demethylation
histone H4-R3 demethylation
blood vessel development
multicellular organism development
chromatin modification
cell differentiation
apoptotic cell clearance
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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