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产品信息
A700-254
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
BLR254L
抗原
Peptide representing a region between residue 100 and 150 of Human Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
purified
保存液
BBS, pH 8.2
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunohistochemistry: Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
靶标信息
This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phagocytosis of apoptotic cells; however, subsequent studies have indicated that it does not directly function in the clearance of apoptotic cells, and questioned whether it is a true phosphatidylserine receptor. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: apoptotic cell clearance receptor PtdSerR; Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; Histone arginine demethylase JMJD6; JmjC domain-containing protein 6; jumonji domain containing 6; Jumonji domain-containing protein 6; Lysyl-hydroxylase JMJD6; Peptide-lysine 5-dioxygenase JMJD6; Phosphatidylserine receptor; Protein PTDSR
基因别名: 5730436I23Rik; D11Ertd195e; JMJD6; KIAA0585; mKIAA0585; PSR; PtdSerR; PTDSR; PTDSR1
UniProt ID: (Human) Q6NYC1, (Mouse) Q9ERI5
Entrez Gene ID: (Human) 23210, (Mouse) 107817
RNA binding
single-stranded RNA binding
receptor activity
iron ion binding
protein binding
histone demethylase activity
histone demethylase activity (H3-R2 specific)
histone demethylase activity (H4-R3 specific)
identical protein binding
protein homodimerization activity
peptidyl-lysine 5-dioxygenase activity
sulfonate dioxygenase activity
oxidoreductase activity
2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity
procollagen-proline dioxygenase activity
hypophosphite dioxygenase activity
DNA-N1-methyladenine dioxygenase activity
metal ion binding
dioxygenase activity
C-19 gibberellin 2-beta-dioxygenase activity
C-20 gibberellin 2-beta-dioxygenase activity
protein modifying enzyme
kidney development
sprouting angiogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
mRNA processing
cell surface receptor signaling pathway
heart development
RNA splicing
peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine
lung development
T cell differentiation in thymus
macrophage activation
recognition of apoptotic cell
regulation of mRNA splicing, via spliceosome
erythrocyte development
oxidation-reduction process
retina development in camera-type eye
histone H3-R2 demethylation
histone H4-R3 demethylation
blood vessel development
multicellular organism development
chromatin modification
cell differentiation
apoptotic cell clearance
