Invitrogen

JNK1/JNK3 Recombinant Rabbit Monoclonal Antibody (ARC1163)

JNK1/JNK3 Antibody in Immunocytochemistry (ICC/IF)

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JNK1/JNK3 Antibody (MA5-35628) in ICC/IF

Immunofluorescence analysis of JNK1/JNK3 in NIH/3T3 cells. Samples were incubated with JNK1/JNK3 Monoclonal antibody (Product # MA5-35628) using a dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

JNK1/JNK3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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产品信息

MA5-35628

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

免疫组化（石蜡） (IHC (P))

1:50-1:200

免疫细胞化学 (ICC/IF)

1:50-1:200

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

ARC1163

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 1-383 of human JNK1 (P45983)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.2 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2849528

产品详细信息

Immunogen sequence: MSRSKRDNNF YSVEIGDSTF TVLKRYQNLK PIGSGAQGIV CAAYDAILER NVAIKKLSRP FQNQTHAKRA YRELVLMKCV NHKNIIGLLN VFTPQKSLEE FQDVYIVMEL MDANLCQVIQ MELDHERMSY LLYQMLCGIK HLHSAGIIHR DLKPSNIVVK SDCTLKILDF GLARTAGTSF MMTPYVVTRY YRAPEVILGM GYKENVDLWS VGCIMGEMVC HKILFPGRDY IDQWNKVIEQ LGTPCPEFMK KLQPTVRTYV ENRPKYAGYS FEKLFPDVLF PADSEHNKLK ASQARDLLSK MLVIDASKRI SVDEALQHPY INVWYDPSEA EAPPPKIPDK QLDEREHTIE EWKELIYKEV MDLEERTKNG VIRGQPSPLG AAV

靶标信息

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrome c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: c-Jun N-terminal kinase 1; c-Jun N-terminal kinase 3; JNK-46; JNK1 beta1 protein kinase; JNK3 alpha protein kinase; JNK3 beta1 protein kinase; JNK3 beta2 protein kinase; JUN N-terminal kinase; MAP kinase 10; MAP kinase 8; MAP kinase p49 3F12; MAPK 10; MAPK 8; mitogen activated protein kinase 10; mitogen activated protein kinase 8; Mitogen-activated protein kinase 10; Mitogen-activated protein kinase 8; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; p54 gamma; p54-beta; protein kinase mitogen-activated 8; SAPK gamma; SAPK-beta; SAPK/Erk/kinase 2; SAPK1b; SAPK1c; Stress activated protein kinase beta; stress-activated protein kinase 1; Stress-activated protein kinase 1b; Stress-activated protein kinase 1c; Stress-activated protein kinase JNK1; Stress-activated protein kinase JNK3

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基因别名: AI849689; C230008H04Rik; JNK; JNK-46; JNK1; JNK1A2; JNK21B1/2; JNK3; JNK3A; JNK3B1; JNK3B2; MAPK10; MAPK8; p493F12; p54bSAPK; PRKM10; PRKM8; SAPb; SAPK(beta); SAPK1; SAPK1B; SAPK1C; SAPKC; Serk2