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JWA Antibody (PA5-109412) in WB
Western blot analysis of JWA in extracts of Mouse thymus. Samples were incubated with JWA Polyclonal antibody (Product # PA5-109412) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
产品信息
PA5-109412
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human ARL6IP5 (NP_006398.1).
偶联物
形式
Liquid
浓度
1.07 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2854823
产品详细信息
Immunogen sequence: TFVMVVMLAS YFLISMFGGV MVFVFGITFP LLLMFIHASL RLRNLKNKLE NKMEGIGLKR TPMGIVLDAL EQQEEGINRL TDYISKVKE
靶标信息
JWA protein expression is affected by vitamin A and may be associated with the cytoskeleton. A protein similar to JWA in rats may play a role in the regulation of cell differentiation by inhibiting the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Addicsin; ADP-ribosylation factor-like protein 6-interacting protein 5; ADP-ribosylation-like factor 6 interacting protein 5; ARL-6-interacting protein 5; Glutamate transporter EAAC1-interacting protein; GTRAP3-18; PRA1 family protein 3; Prenylated Rab acceptor protein 2; Protein JWa
基因别名: 5930404D22Rik; addiscin; Aip-5; Aip5; Arl6ip5; AV001879; Gtrap3-18; Jwa; Pra2; Praf3
UniProt ID: (Mouse) Q8R5J9
Entrez Gene ID: (Mouse) 65106
intrinsic apoptotic signaling pathway in response to oxidative stress
negative regulation of mitochondrial membrane potential
L-glutamate transport
positive regulation of stress-activated MAPK cascade
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of transport
