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产品信息
PA5-62333
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2642869
产品详细信息
Immunogen sequence: QLREATTQTP WSCAEKAAQT ESPAEAPSLT QESSPGSMDG DRAVAPAGIL KSIMK
Highest antigen sequence identity to the following orthologs: Mouse - 45%, Rat - 51%.
靶标信息
Ankyrins are membrane adaptor molecules that play important roles in the control of cytoskeleton formation by regulating actin polymerization. Like other members of the KANK family, KANK3 (KN motif and ankyrin repeat domain-containing protein 3), is thought to play a role in the formation of actin stress fibers. In zebrafish, the homolog of KANK3 interacts with the adaptor protein Numb, a protein implicated in multiple basic cellular processes, and is essential for epidermal integrity and neurulation, suggesting that KANK3 may play a similar role in higher organisms.
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生物信息学
蛋白别名: ankyrin repeat domain 47; Ankyrin repeat domain-containing protein 47; kidney ankyrin repeat-containing protein 3; KN motif and ankyrin repeat domain-containing protein 3
基因别名: ANKRD47; KANK3
UniProt ID: (Human) Q6NY19
Entrez Gene ID: (Human) 256949
