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产品信息
PA5-89426
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 298-597 of human LysRS/LysRS/KARS (NP_0055391)
偶联物
形式
Liquid
浓度
3.14 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805566
产品详细信息
Immunogen sequence: IAPELYHKML VVGGIDRVYE IGRQFRNEGI DLTHNPEFTT CEFYMAYADY HDLMEITEKM VSGMVKHITG SYKVTYHPDG PEGQAYDVDF TPPFRRINMV EELEKALGMK LPETNLFETE ETRKILDDIC VAKAVECPPP RTTARLLDKL VGEFLEVTCI NPTFICDHPQ IMSPLAKWHR SKEGLTERFE LFVMKKEICN AYTELNDPMR QRQLFEEQAK AKAAGDDEAM FIDENFCTAL EYGLPPTAGW GMGIDRVAMF LTDSNNIKEV LLFPAMKPED KKENVATTDT LESTTVGTSV; Positive Samples: HepG2, Jurkat, HeLa, 293T, Mouse heart, Mouse kidney, Rat liver; Cellular Location: Cell membrane, Cytoplasm, Mitochondrion, Nucleus, Peripheral membrane protein
靶标信息
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: EC 6.1.1.6; lysine tRNA ligase; Lysine--tRNA ligase; LysRS; Lysyl-tRNA synthetase
基因别名: AA589550; AL024334; AL033315; AL033367; CMTRIB; D8Ertd698e; D8Wsu108e; DFNB89; KARS; KARS1; KARS2; KIAA0070; KRS; LysRS; mKIAA0070
UniProt ID: (Human) Q15046, (Rat) Q5XIM7, (Mouse) Q99MN1
Entrez Gene ID: (Human) 3735, (Rat) 292028, (Mouse) 85305
