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MA5-15426 targets KARS in indirect ELISA, IHC and WB applications and shows reactivity with Human samples.
The MA5-15426 immunogen is purified recombinant fragment of KARS(aa90-174) expressed in E. Coli.
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Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: EC 6.1.1.6; lysine tRNA ligase; Lysine--tRNA ligase; LysRS; Lysyl-tRNA synthetase
基因别名: CMTRIB; DFNB89; KARS; KARS1; KARS2; KIAA0070; KRS
UniProt ID: (Human) Q15046
Entrez Gene ID: (Human) 3735