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KBTBD3 Antibody (PA5-32116) in IHC (P)
KBTBD3 Polyclonal Antibody detects KBTBD3 protein at cytoplasm on human lung carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded lung carcinoma. KBTBD3 Polyclonal Antibody (Product # PA5-32116) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
产品信息
PA5-32116
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein fragment corresponding to a region within amino acids 11 and 268 of Human KBTBD3
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2549589
产品详细信息
Recommended positive controls: PC-3.
Predicted reactivity: Mouse (89%), Rat (88%), Rhesus Monkey (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The BTB (Broad-Complex, Tram track and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. KBTBD3 (kelch repeat and BTB domain-containing protein 3), also known as BKLHD3, is a 608 amino acid protein that contains one BACK (BTB/Kelch associated) domain, one BTB (POZ) domain and five kelch repeats. The gene encoding KBTBD3 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BTB and kelch domain containing 3; BTB and kelch domain-containing protein 3; kelch repeat and BTB (POZ) domain containing 3; Kelch repeat and BTB domain-containing protein 3
基因别名: BKLHD3; KBTBD3
UniProt ID: (Human) Q8NAB2
Entrez Gene ID: (Human) 143879
