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KCC4 Antibody (PA5-88472) in WB
Western blot analysis of KCC4 in extracts of various cell lines. Samples were incubated with KCC4 Polyclonal antibody (Product # PA5-88472) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
产品信息
PA5-88472
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human SLC12A7 (NP_0065892)
偶联物
形式
Liquid
浓度
1.02 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2804934
产品详细信息
Immunogen sequence: MPTNFTVVPV EAHADGGGDE TAERTEAPGT PEGPEPERPS PGDGNPRENS PFLNNVEVEQ ESFFEGKNMA; Positive Samples: Mouse kidney, Mouse liver, Rat kidney; Cellular Location: Cell membrane, Multi-pass membrane protein
靶标信息
Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification. [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Electroneutral potassium-chloride cotransporter 4; furosemide-sensitive KCl cotransporter 4; K-Cl cotransporter 4; K-Cl cotransporter KCC4; slc12a7 {ECO:0000312|EMBL:AAH86339.1, ECO:0000312|RGD:1359672}; solute carrier family 12 (potassium/chloride transporters), member 7; Solute carrier family 12 member 7
基因别名: AA408796; D13Ertd261e; Kcc4; Slc12a7
UniProt ID: (Rat) Q5RK27, (Mouse) Q9WVL3
Entrez Gene ID: (Rat) 308069, (Mouse) 20499
